Manipulating Surface Topography for Better Integration

Submitted on Wed, 06/14/2023

Guillermo Ameer

Working at the convergence of the physical sciences, biology, surgery, and engineering,  an interdisciplinary team from Northwestern Engineering’s Center for Advanced Regenerative Engineering (CARE) and Center for Physical Genomics and Engineering (CPGE) introduced the concept of surface topography-induced chromatin engineering. In a collaboration with The University of Chicago’s Russell R. Reid and Tong-Chuan He, the team explained how and why to use surfaces to change patterns, validating the method in vivo. The findings could potentially lead to new design strategies for biomedical companies to improve the performance of implantable medical devices that promote or require new bone formation.

Read the full press release here.